Anaerobic Porphyrin Biosynthesis.
نویسندگان
چکیده
منابع مشابه
Biosynthesis of Porphyrin Precursors
Bovine liver mitochondria have been found to contain an enzyme which will catalyze the formation of &aminolevulinic acid via a transamination reaction rather than via the condensation of glycine and succinyl coenzyme A. The enzyme, L-alanine:y,bdioxovaleric acid aminotransferase (y,&dioxovalerate transaminase) was isolated and purified to apparent homogeneity. y,&Dioxovalerate transaminase is q...
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6-Aminolevulinic acid synthase has been purified 1300-fold from photosynthetically cultured Rhodopseudomonas spheroides. The enzyme having a specific activity of 130 units per mg shows one major band and two minor bands upon disc electrophoresis. Some properties, including molecular weight, stability, and the inhibition of enzyme activity by hemin are reported. The comparative behavior of crude...
متن کاملPorphyrin Biosynthesis in Erythrocytes
The porphyrinogens are colorless, reduced porphyrins containing 6 extra atoms of hydrogen. They have been reported to occur in biological materials by Fischer, who isolated COPRO’gen’ from the feces of his porphyria patient Petry (l), and by Watson, Schwartz, and coworkers, who showed that COPRO’gen was present in the urine of some of their patients with various porphyrias (2). Suspicions that ...
متن کاملA Comparative Study of Porphyrin Biosynthesis
LTHOUGH the primary precursors, the intermediates and most of the enzymes involved ir the biosynthetic chain of porphyrins are now known,’,2’3 knowledge of the tissue sites( s) of porphyrin formation is incomplete. Several earlier studies4’5 demonstrated that avian nucleated erythrocytes as well as rabbit bone marrow are active in this respect. Both tissues utilize either glycine and acetate ( ...
متن کاملPorphyrin Biosynthesis in Normal and Haem
Heine biosynthesis was studied in the segregants of Saccharomyces cerevisiae (DW10 tetrade 2) from D27 and D27/C6 mating, as a function of the carbon source in the growth medium and the physiological state of the cells. The effects of the HEM R+ gene on the 5-aminolevulinate synthase (ALA-S) and 5-aminolevulinate dehydratase (ALA-D) activities of heine biosynthesis in cells grown on nonfermenta...
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ژورنال
عنوان ژورنال: Journal of Synthetic Organic Chemistry, Japan
سال: 1996
ISSN: 0037-9980,1883-6526
DOI: 10.5059/yukigoseikyokaishi.54.176